Microporous surface as a new solution for stent surface modification: A review

The introduction of coronary stents into clinical practice has reduced repeated patient visits compared with balloon angioplasty alone. Also, drug-eluting substantially the restenosis incidence. Therefore, later complications related to implantation a stent coated cytostatic-containing polymer became more relevant. mechanism late is multifactorial. It mainly due body's response prolonged indwelling drug carrier on stent's surface. There trend towards return polymer-free coating technologies, which are implemented through certain modifications surfaces for better retention and proper distribution. achieved using depots in various reservoirs: grooves, nanoparticles matrix compound, micropores, blind micro reservoirs, etc. New promising technologies crystallizing cytostatic drugs or depositing them specially designed reservoirs show good preclinical results, comparable even superior approved stents. Micropores as carriers antiproliferative agents surface direction rejecting use polymers